Research News

UK Begins 1st Clinical Trial in the World for Newly Discovered Form of Dementia

Mar 16, 2022, 7:10 AM

The world’s first clinical trial for a form of dementia identified in 2019 is officially underway by researchers at the University of Kentucky's Sanders-Brown Center on Aging.

Results of Johnson & Johnson COVID-19 Vaccine Trial Announced

Feb 1, 2021, 1:44 PM

The Phase 3 randomized, double-blind, placebo-controlled clinical trial was designed to evaluate the safety and efficacy of a single vaccine dose of the Janssen investigational COVID-19 vaccine candidate versus placebo. Approximately 45,000 people participated worldwide. The combined UK, Baptist and Norton site was among the top enrolling sites in the world.

Markey Study Shows Kentucky Endometrial Cancer Patients Have Higher Rates of DACH1 Mutation

Jan 12, 2021, 8:18 AM

A new study by UK Markey Cancer Center researchers shows that DACH1 mutations are prevalent in Kentucky patients with endometrial cancer, suggesting that DACH1 may be a candidate biomarker for future trials with immunotherapy.

'Behind the Blue': Dr. Peter Nelson Discusses UK’s Leading Efforts on Alzheimer’s and Dementia Research

Nov 20, 2020, 8:27 AM

Dr. Peter Nelson, of the University of Kentucky’s Sanders-Brown Center on Aging, has spent the last 15 years in the Commonwealth helping to lead the fight against Alzheimer’s and dementia inducing brain disease.

UK and Baptist Health Lexington, Norton Health Care Begin Recruiting Participants for Phase 3 COVID-19 Investigational Vaccine Clinical Trial

Nov 5, 2020, 11:09 AM

Janssen’s AdVac® technology was used to develop Janssen’s Ebola vaccine regimen and is the basis for its HIV, RSV and Zika vaccine candidates.

UK Study Shows FDA-approved Leukemia Drug May Help Treat Metastatic Melanoma

Oct 29, 2020, 8:29 AM

Building on these findings, Plattner and Markey oncologists are now collaborating with the pharmaceutical company Novartis to develop a Phase I clinical trial to test the safety and effectiveness of using nilotinib in relapsed melanoma patients.

Health Sciences Team Leading $2.5 Million Multi-Site Ankle Injury Research Project

Oct 22, 2020, 8:18 AM

A team of Health Sciences investigators are collaborating with military researchers at the Naval Health Research Center and faculty at the University of Virginia to find rehabilitative solutions for populations most at risk for chronic and future ankle injuries.

College of Pharmacy Receives $11.8 Million to Further Substance Use Disorder Research

Sep 8, 2020, 8:24 AM

The funding will further ongoing substance use disorder treatment research in collaboration with Sharon Walsh at the UK Center on Drug and Alcohol Research (CDAR) and Mei-Chuan Ko at the Wake Forest School of Medicine.

Cancer, COVID and the Kentucky Economy: How 'Sweet Annie' Could Make an Impact

Aug 11, 2020, 8:19 AM

Artemisia annua or "Sweet Annie" has been used as a medicinal herb for centuries. With potential to treat a variety of cancers & even COVID-19, this plant is more relevant than ever & UK is showing how we can take it from Kentucky fields to the lab to our patients.

Volunteers Needed for Survey on Sleep, Stress, Alcohol Use During COVID-19 Outbreak

Aug 3, 2020, 8:23 AM

UK researchers hope to gain a better understanding of the effects of COVID-19 on sleep and alcohol use so that we will be better prepared to prevent and treat psychological effects of COVID-19 pandemic or similar outbreaks in the future.

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