Research News

Sanders-Brown Research Discovers New Pathway in TDP-43 Related Dementias

Sep 23, 2020, 9:46 AM

Selenica says their study is the first to provide a novel pathway and identify potential therapeutic targets for TDP-43 proteinopathies – especially in Alzheimer’s disease and the newly characterized form of dementia known as LATE.

Sanders-Brown Study Leads to Potential New Treatment Approach for Alzheimer’s Disease

Aug 25, 2020, 8:18 AM

Through the group's work, they found that the therapeutic targeting of TREM2 using a TREM2-activating antibody leads to the activation of microglia, recruitment of microglia to amyloid plaques, reduced amyloid deposition, and ultimately improved cognition.

UK’s Sanders-Brown, Penn Researchers Provide Insights into Newly Characterized Form of Dementia

Aug 25, 2020, 8:12 AM

“We used to think that aging-related memory and thinking decline meant one thing: a disease called Alzheimer’s disease. Now we know that the disease we were calling Alzheimer’s disease is actually many different conditions, often in combination."

UK Research Center Establishes Scholar Program to Promote Diversity in Neurotrauma Studies

Aug 6, 2020, 8:33 AM

Prendergast says statistics show that less than five percent of undergraduate neuroscience students in the U.S. are Black or African American, but at UK nearly ten percent of undergraduate neuroscience majors identify as Black or African American.

Important Dementia Studies Continuing at UK Despite Ongoing COVID-19 Pandemic

Jul 30, 2020, 8:36 AM

Researchers will be looking at a medication that recently received experimental approval from the USDA and its impact on the newly characterized form of dementia known as LATE. LATE is a disease with symptoms similar to Alzheimer’s disease.

Researchers Publish Study Looking at Approaches to Better Treat Alzheimer's Disease

Jul 29, 2020, 8:34 AM

For the past several decades, much of the work to find a treatment for AD has been focused on eliminating those dreaded Aβ plaques, by assuming that memory could be restored by removing the plaques.

UK Receives $3.2 Million for Traumatic Brain Injury Research

Jul 21, 2020, 1:05 PM

The National Institutes of Health award will fund ongoing research led by UK Neuroscience and Spinal Cord and Brain Injury Research Center (SCoBIRC) Professor Patrick Sullivan, Ph.D., who has studied the effects of the experimental drug MP201 on TBI.

UK Sanders-Brown Center on Aging Facilitates First Participant in Worldwide Drug Study

Jul 17, 2020, 8:21 AM

This work is looking at a study medication, BAN2401, to determine if it can help prevent worsening memory and thinking among individuals who might be at risk for future decline. They are hoping it will ultimately help prevent Alzheimer’s disease.

Sanders-Brown Researcher Receives Grant Supported by Rotary Clubs to Further Dementia Studies

Jul 8, 2020, 8:26 AM

The $125,000 grant comes from The CART Fund. CART (Coins for Alzheimer’s Research Trust) is a grassroots effort by Rotary Club members throughout the country to provide cutting edge research to help find a cure for Alzheimer’s.

It’s Not Just Alzheimer’s Disease: Sanders-Brown Research Highlights Form of Severe Dementia

Jun 29, 2020, 8:24 AM

The long-running study on aging and brain health at UK’s Sanders-Brown Center on Aging (SBCoA) Alzheimer’s Disease Center has once again resulted in important new findings – highlighting a complex and under-recognized form of dementia.

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