Research News

Sanders-Brown Study Leads to Potential New Treatment Approach for Alzheimer’s Disease

Aug 25, 2020, 8:18 AM

Through the group's work, they found that the therapeutic targeting of TREM2 using a TREM2-activating antibody leads to the activation of microglia, recruitment of microglia to amyloid plaques, reduced amyloid deposition, and ultimately improved cognition.

UK’s Sanders-Brown, Penn Researchers Provide Insights into Newly Characterized Form of Dementia

Aug 25, 2020, 8:12 AM

“We used to think that aging-related memory and thinking decline meant one thing: a disease called Alzheimer’s disease. Now we know that the disease we were calling Alzheimer’s disease is actually many different conditions, often in combination."

Important Dementia Studies Continuing at UK Despite Ongoing COVID-19 Pandemic

Jul 30, 2020, 8:36 AM

Researchers will be looking at a medication that recently received experimental approval from the USDA and its impact on the newly characterized form of dementia known as LATE. LATE is a disease with symptoms similar to Alzheimer’s disease.

It’s Not Just Alzheimer’s Disease: Sanders-Brown Research Highlights Form of Severe Dementia

Jun 29, 2020, 8:24 AM

The long-running study on aging and brain health at UK’s Sanders-Brown Center on Aging (SBCoA) Alzheimer’s Disease Center has once again resulted in important new findings – highlighting a complex and under-recognized form of dementia.

UK Researcher Makes 'Top Science Stories of 2019' List by Discover Magazine

Jan 16, 2020, 8:03 AM

An international group of experts led by Dr. Peter Nelson, a neuropathologist at the UK Sanders-Brown Center on Aging, is being recognized as one of the top science stories of 2019 by Discover Magazine.

Antibiotics Could Be Promising Treatment for Form of Dementia

Jan 10, 2020, 8:16 AM

Researchers at UK's College of Medicine have found that a class of antibiotics could be promising treatment for a form of dementia. Results of their proof of concept study were recently published in the journal Human Molecular Genetics.

When is Alzheimer's Not Alzheimer's? Researchers Characterize a Different Form of Dementia

May 1, 2019, 10:36 AM

In the past, using "Alzheimer’s disease" & "dementia" interchangeably was a generally accepted practice. Now there's rising appreciation that a variety of diseases & disease processes contribute to dementia.

A Low Dose Aspirin for Dementia? Drug Ready for Human Testing

Apr 3, 2019, 9:25 AM

Linda Van Eldik, director of the UK Sanders-Brown Center on Aging, received $5.5 million from NIH and the Alzheimer's Drug Discovery Foundation. She developed a drug that is ready for its first round of testing in humans.

Does Smoking Cause Dementia? Maybe Not, Study Says

Mar 26, 2019, 8:48 AM

It's an irrefutable fact that smoking is bad for you. Study after study has proven that smoking increases your risk for cancer, heart disease, diabetes – even blindness. But dementia? Not so fast. A recent study has demonstrated that smoking is not associated with a higher risk of dementia.

Research Identifies Potential Predictors of Vascular Cognitive Impairment and Dementia in Alzheimer's

Nov 7, 2018, 9:31 AM

Research from the Sanders-Brown Center on Aging presented at the Society for Neuroscience annual meeting has identified two potential ways to predict vascular cognitive impairment and dementia (VCID) – the second leading cause of dementia behind Alzheimer's disease.

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