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Sanders-Brown Study Leads to Potential New Treatment Approach for Alzheimer’s Disease

Through the group's work, they found that the therapeutic targeting of TREM2 using a TREM2-activating antibody leads to the activation of microglia, recruitment of microglia to amyloid plaques, reduced amyloid deposition, and ultimately improved cognition.

UK’s Sanders-Brown, Penn Researchers Provide Insights into Newly Characterized Form of Dementia

“We used to think that aging-related memory and thinking decline meant one thing: a disease called Alzheimer’s disease. Now we know that the disease we were calling Alzheimer’s disease is actually many different conditions, often in combination."

UK Research Center Establishes Scholar Program to Promote Diversity in Neurotrauma Studies

Prendergast says statistics show that less than five percent of undergraduate neuroscience students in the U.S. are Black or African American, but at UK nearly ten percent of undergraduate neuroscience majors identify as Black or African American.

Important Dementia Studies Continuing at UK Despite Ongoing COVID-19 Pandemic

Researchers will be looking at a medication that recently received experimental approval from the USDA and its impact on the newly characterized form of dementia known as LATE. LATE is a disease with symptoms similar to Alzheimer’s disease.

UK Receives $3.2 Million for Traumatic Brain Injury Research

The National Institutes of Health award will fund ongoing research led by UK Neuroscience and Spinal Cord and Brain Injury Research Center (SCoBIRC) Professor Patrick Sullivan, Ph.D., who has studied the effects of the experimental drug MP201 on TBI.

UK Receives Prestigious Grant from National Institute of Neurological Disorders

The work at UK in Gentry’s lab supported by this award will focus on novel insights in energy metabolism using cutting edge methodologies applied to multiple human diseases.

Sanders-Brown Director Leads First Human Study of Drug Targeting Brain Inflammation

Linda J. Van Eldik, director of the Sanders-Brown Center on Aging at UK, co-authored a paper reporting the first human clinical study of a drug candidate that suppresses injury and disease-induced inflammation of the brain.

Free Radical Discovery a Hallmark of Allan Butterfield’s 45-Year Research Career

When you look back at a 45-year career, there are a multitude of moments that stand out. For Allan Butterfield, Professor of Biological Chemistry in the UK College of Arts & Sciences, his signature discovery grew from just such a Eureka moment on the sidewalk on campus. 

Kitzman Receives National Award for Outstanding Advocacy in Neurologic Therapy

“I can’t advocate for someone unless I’m working with them. It’s presumptuous to say, ‘I know what you need,’” Kitzman said. “The moment we at KARRN start working with someone, we agree to be their advocate and do whatever it takes to find resources for them.”

UK Research Could Help Predict Progression of Parkinson's Disease

A pilot grant from UK’s Center for Clinical and Translational Science (CCTS) will advance neuroscience researcher George Quintero’s studies on Parkinson’s disease to a clinical investigation.

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