Special Biology Research Talk: "Genomic Regulation of Retinal Development and Disease"

Presenter: Dr. Anand Swaroop, from the National Eye Institute

Faculty Host: Dr. Ann Morris

   

Abstract:

Multiple levels of control mechanisms exist for spatio-temporal and context-dependent expression of genetic information during development and for maintaining cellular homeostasis. Any disruption in gene regulatory networks can lead to disease phenotypes. I will first discuss NRL-mediated transcriptional control network guiding photoreceptor differentiation and then examine gene regulation by genomic architecture in developing retina. Time permitting, I will also discuss how genetic variants in the non-coding genome can influence complex phenotypes including AMD and glaucoma.

Learn more: https://bio.as.uky.edu/biology-research-talk-7