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Multi-Million Dollar Multidisciplinary Grant Supports Advancement of Epilepsy Research

A $2.9 million grant from the NIH is supporting a multidisciplinary team of UK researchers in continuing their work to find therapeutic strategies to resolve neurovascular inflammation and repair blood-brain barrier dysfunction in epilepsy.

10th Annual Sanders-Brown Markesbery Symposium on Aging and Dementia Taking Place Virtually

In the sessions for both the scientific and community audience, attendees will have the opportunity to hear clinicians and researchers from UK and other institutions share current findings, trends, and latest updates on dementia and aging disorders.

Butterfield Recognized as a Leading Alzheimer’s Expert

Butterfield is among the top 0.007% of scholars worldwide based on authorship of Alzheimer’s-related publications indexed in the PubMed database for the past 10 years. He ranks tenth out of nearly 150,000 scholars worldwide and sixth in the U.S.

New Study Looks at Encoding the Odor of Cigarette Smoke

In addition to opening the door to developing blockers of odors, McClintock says this work will help researchers understand why formulating fragrances and flavors with specific properties is so difficult. “Ergo, the oft-used phrase 'the art of perfumery.' Eventually, we will turn this art into science.”

Sanders-Brown Research Discovers New Pathway in TDP-43 Related Dementias

Selenica says their study is the first to provide a novel pathway and identify potential therapeutic targets for TDP-43 proteinopathies – especially in Alzheimer’s disease and the newly characterized form of dementia known as LATE.

Sanders-Brown Study Leads to Potential New Treatment Approach for Alzheimer’s Disease

Through the group's work, they found that the therapeutic targeting of TREM2 using a TREM2-activating antibody leads to the activation of microglia, recruitment of microglia to amyloid plaques, reduced amyloid deposition, and ultimately improved cognition.

UK’s Sanders-Brown, Penn Researchers Provide Insights into Newly Characterized Form of Dementia

“We used to think that aging-related memory and thinking decline meant one thing: a disease called Alzheimer’s disease. Now we know that the disease we were calling Alzheimer’s disease is actually many different conditions, often in combination."

UK Research Center Establishes Scholar Program to Promote Diversity in Neurotrauma Studies

Prendergast says statistics show that less than five percent of undergraduate neuroscience students in the U.S. are Black or African American, but at UK nearly ten percent of undergraduate neuroscience majors identify as Black or African American.

Important Dementia Studies Continuing at UK Despite Ongoing COVID-19 Pandemic

Researchers will be looking at a medication that recently received experimental approval from the USDA and its impact on the newly characterized form of dementia known as LATE. LATE is a disease with symptoms similar to Alzheimer’s disease.

Researchers Publish Study Looking at Approaches to Better Treat Alzheimer's Disease

For the past several decades, much of the work to find a treatment for AD has been focused on eliminating those dreaded Aβ plaques, by assuming that memory could be restored by removing the plaques.

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